Botanical drugs are complex mixtures of different compounds. All the elements of their production affect the final composition of the drug. This includes the species and strains used, the growing and harvesting conditions, and the manufacturing methods. These are protected through patents or as trade secrets.
Psilocybin is a well-known compound found in magic mushrooms.
It is not bioactive in humans; it must convert into psilocin in order to cause hallucinogenic and therapeutic effects.
Bypassing this conversion by directly administering psilocin could mean faster onset time, fewer side effects, and more consistent dosing, but to date, it has never been done.
This is because psilocin is unstable, particularly when manufactured synthetically. To overcome this instability researchers have historically produced synthetic psilocybin, which is more stable.